Streptomyces peucetius subsp. caesius Arcamone et al.
商品貨號(hào)
B227655
Strain Designations
IMRU 3920 [FI 186, IPV 1946]
Application
Produces FCE 21424
Produces FCE 24366
Produces FCE 24367
Produces doxorubicin adriamycin
Produces antineoplastic agents FCE 21424, FCE 24366 and FCE 24367
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
freeze-dried
Storage Conditions
Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
Preceptrol®
no
Type Strain
no
Comments
Synthase genes for daunorubicin/doxorubicin
Medium
ATCC® Medium 1877: ISP Medium 1
ATCC® Medium 196: Yeast malt extract agar
Growth Conditions
Temperature: 26°C
Atmosphere: Aerobic
Name of Depositor
RE Gordon
Chain of Custody
ATCC <-- RE Gordon <-- B. Camerino, Farmitalia FI 106
References
Cassinelli G, et al. New biosynthetic anthracyclines related to barminomycins incorporating barbiturates in their moiety. J. Antibiot. 43: 19-28, 1990. PubMed: 2307627
Arcamone F, et al. Adriamycin derivatives. US Patent 3,590,028 dated Jun 29 1971
Stutzman-Engwall KJ, Hutchinson CR. Multigene families for anthracycline antibiotic production in Streptomyces peucetius. Proc. Natl. Acad. Sci. USA 86: 3135-3139, 1989. PubMed: 2717612
